Publications by authors named "Amy J McGowan"
Retinal microvascular network attenuation in Alzheimer's disease.
Alzheimers Dement (Amst)
June 2015
Article Synopsis
- Cerebral small-vessel disease is linked to Alzheimer's disease (AD), and this study investigates retinal microvascular changes in AD patients compared to cognitively normal individuals.
- Researchers analyzed retinal images to measure parameters like caliber, fractal dimension, tortuosity, and bifurcation, using regression models to assess the relationship between these parameters and AD risk.
- The study found that lower venular fractal dimension and arteriolar tortuosity were associated with a higher likelihood of having AD, suggesting that changes in the retinal microvascular network may reflect similar issues in the brain's microvasculature.
Purpose: With the increasing global prevalence of childhood obesity, it is important to have appropriate measurement tools for investigating factors (e.g., sedentary time) contributing to positive energy balance in early childhood.
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