Publications by authors named "Amy E Nilles"
Article Synopsis
- The mitochondria-ER cortex anchor (MECA) is essential for the proper positioning and function of mitochondria by connecting them to the plasma membrane.
- The key protein in MECA is Num1, which forms clusters in the cell cortex and has a unique structure that allows it to interact with both mitochondria and the plasma membrane.
- Num1's ability to bind to specific lipids, like cardiolipin found in mitochondria, is crucial for its role in anchoring mitochondria, indicating a broader mechanism for linking different organelles.
