Publications by authors named "Amy Dong"
Article Synopsis
- - This pilot study aimed to explore the changes in vaginal microbial communities in African American women before the onset of incident bacterial vaginosis (iBV) using advanced shotgun metagenomic sequencing methods.
- - Results showed that certain bacteria associated with BV, like G. vaginalis and Fannyhessea vaginae, increased significantly, while beneficial Lactobacillus species decreased leading up to iBV.
- - The study highlights critical bacterial dynamics and potential mechanisms involved in the development of iBV, contributing to the understanding of this common condition.
Summary: Eukaryotic gene expression requires coordination among hundreds of transcriptional regulators. To characterize a specific transcriptional regulator, identifying how it shares genomic-binding sites with other regulators can generate important insights into its action. As genomic data such as chromatin immunoprecipitation assays with sequencing (ChIP-Seq) are being continously generated from individual labs, there is a demand for timely integration and analysis of these new data.
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