Publications by authors named "Amy B Funk"
Reprod Toxicol
November 2006
Article Synopsis
- DEGME, EGME, and their metabolite MAA have been linked to negative reproductive effects, prompting research into their impact on cartilage cell development (chondrogenesis).
- In lab experiments, all three substances reduced proteoglycan levels and cell growth at higher concentrations, but only MAA consistently showed stronger effects at lower doses.
- The study suggests that DEGME and EGME cause general toxicity, while MAA specifically triggers cell death through a process called mitochondrial-mediated apoptosis.
