Publications by authors named "Amy Aponte"

Unlabelled: Breast cancer subtypes and their phenotypes parallel different stages of the mammary epithelial cell developmental hierarchy. Discovering mechanisms that control lineage identity could provide novel avenues for mitigating disease progression. Here we report that the transcriptional corepressor TLE3 is a guardian of luminal cell fate in breast cancer and operates independently of the estrogen receptor.

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Article Synopsis
  • Zebrafish are increasingly used as a model for studying stress effects due to similarities with mammals' neural and biochemical systems.
  • A study aimed to investigate the impact of acute net handling stress on cortisol levels and anxiety-like behaviors in young adult zebrafish, but found no significant effects.
  • The results imply that developmental differences may impact how zebrafish respond to stress, suggesting a need for alternative stressors or methods to better understand the neuroendocrine mechanisms involved.
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