Background: Ligamentum arteriosum calcification may be a normal finding in some children, although the frequency has not been well described.
Objective: To estimate the frequency of ligamentum arteriosum calcification in children at postmortem imaging.
Materials And Methods: We conducted a single-centre retrospective review of paediatric postmortem CT and chest radiographic imaging over a 6-year period (January 2012 to December 2018).
We present three cases of choledocholithiasis presenting with a rise in transaminase to levels normally associated with acute hepatitis (alanine aminotransferase in excess of 1000 IU/l). All three cases had repeated investigation for liver disease before identification of common bile duct stones with magnetic resonance cholangiopancreatogram, and removal at endoscopic retrograde cholangiopancreatogram. We discuss the existing literature and the potential mechanisms of hepatocyte injury in extrahepatic obstruction.
View Article and Find Full Text PDF