Publications by authors named "Amwm Aarts"
Background: The major goal of routine follow-up in oropharyngeal squamous cell carcinoma (OPSCC) patients is the asymptomatic detection of new disease in order to improve survival. This study evaluated the effect of routine follow-up on overall survival (OS).
Methods: A retrospective cohort of 307 consecutive OPSCC patients treated with curative intent between 2006 and 2012 was analyzed.
Objectives: The aim of this study was to provide an overview of published mathematical estimation approaches to quantify the duration of the preclinical detectable phase (PCDP) using data from cancer screening programs.
Methods: A systematic search of PubMed and Embase was conducted for original studies presenting mathematical approaches using screening data. The studies were categorized by mathematical approach, data source, and assumptions made.
Article Synopsis
- This study aims to establish evidence-based follow-up intervals for breast cancer survivors by assessing the sensitivity of clinical breast examination (CBE) and mammography for detecting new cancers.
- The analysis involved 589 women diagnosed with contralateral second breast cancers (CBC) in Florence, utilizing an exponential model to estimate test sensitivities and preclinical detectable phases (PCDP) stratified by age and follow-up periods.
- Results indicated that while mammography demonstrated high sensitivity (91%) and a longer PCDP (35 months), CBE showed lower sensitivity (55%) and a shorter PCDP (16 months), suggesting that mammography may be a more effective screening method, especially for older women and those with longer follow-up periods.