Incidence of leukocytoclastic vasculitis, 1996 to 2010: a population-based study in Olmsted County, Minnesota.

Objective: To determine the population-based incidence of leukocytoclastic vasculitis (LCV).

Patients And Methods: This is a retrospective population-based study of all Olmsted County, Minnesota, residents with a skin biopsy-proven diagnosis of LCV from January 1, 1996, through December 31, 2010.

Results: A total of 84 patients (mean age at diagnosis, 48.

A vitamin D analogue inhibits colonic carcinogenesis in the AOM/DSS model.

Background: The azoxymethane (AOM) model recapitulates many features of human colon cancer, lacking an inflammatory component. Dextran sulfate sodium (DSS) induces colitis and promotes AOM-induced colon cancer in mice. Vitamin D analogues are anti-inflammatory and chemopreventive in models of colon cancer.