Publications by authors named "Amrhein T"

Article Synopsis
  • Spontaneous intracranial hypotension is primarily caused by spinal CSF leaks, mostly reported in adults, but this report focuses on its occurrence in children.
  • Recent advances in specialized myelography techniques have improved the localization of these leaks, yet there's been limited research in the pediatric population due to the rarity of the condition and concerns about invasive procedures.
  • This study reviews pediatric cases with spontaneously occurring spinal CSF leaks, identifying similar leak types found in adults, and demonstrates that advanced imaging techniques can effectively pinpoint and aid in the treatment of these leaks.
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Article Synopsis
  • This study investigates factors affecting the visibility of CSF-venous fistulas (CVF) on specialized myelographic imaging, focusing on timing of imaging and contrast density.
  • A cohort of 24 patients with spontaneous intracranial hypotension underwent 34 CT myelographies to analyze the relationship between contrast density in the subarachnoid space and visibility of CVFs.
  • Results indicate that higher contrast density significantly correlates with better visibility of CVFs, whereas the timing of imaging does not have a significant impact on their visibility.
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Spinal CSF leak care has evolved during the past several years due to pivotal advances in its diagnosis and treatment. To the reader of the (), it has been impossible to miss the exponential increase in groundbreaking research on spinal CSF leaks and spontaneous intracranial hypotension (SIH). While many clinical specialties have contributed to these successes, the neuroradiologist has been instrumental in driving this transformation due to innovations in noninvasive imaging, novel myelographic techniques, and image-guided therapies.

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Background And Purpose: Early opacification of the renal collecting system during CT myelography (CTM) performed for the evaluation of spontaneous intracranial hypotension (SIH) has been demonstrated in prior studies. However, these investigations often included CTMs scanned >30 minutes after intrathecal contrast injection, a longer delay than the myelographic techniques used in current practice. The purpose of this study was to determine whether renal contrast excretion (RCE) measured during this earlier time period (≤30 minutes) can discriminate patients with SIH from patients without SIH.

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Article Synopsis
  • CSF-venous fistulas (CVFs) are a common cause of spontaneous intracranial hypotension, but they are challenging to detect through imaging methods.
  • Since their identification in 2014, the awareness and diagnosis of CVFs have improved significantly due to collaboration across multiple institutions.
  • This article reviews various imaging techniques for detecting CVFs, highlighting their specific benefits and limitations, and discusses strategies to enhance imaging visibility through specialized positions and techniques.
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Background: The rise of minimally invasive lumbar fusions and advanced imaging technologies has facilitated the introduction of novel surgical techniques with the trans-facet approach being one of the newest additions. We aimed to quantify any pathology-driven anatomic changes to the trans-facet corridor, which could thereby alter the ideal laterality of approach to the disc space.

Methods: In this retrospective cohort study, we measured the areas and maximum permissible cannula diameters of the trans-facet corridor using commercially available software (BrainLab, Munich, Germany).

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Background And Purpose: Various imaging techniques have been described to detect CSF-venous fistulas in the setting of spontaneous intracranial hypotension, including decubitus CT myelography. The expected diagnostic yield of decubitus CT myelography for CSF-venous fistula detection is not fully established. The purpose of this study was to assess the yield of decubitus CT myelography among consecutive patients presenting for evaluation of possible spontaneous intracranial hypotension and to examine the impact of brain MR imaging findings of spontaneous intracranial hypotension on the diagnostic yield.

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Purpose Of Review: This review focuses on the challenges of diagnosing and treating spontaneous intracranial hypotension (SIH), a condition caused by spinal CSF leakage. It emphasizes the need for increased awareness and advocates for early and thoughtful use of empirical epidural blood patches (EBPs) in suspected cases.

Recent Findings: SIH diagnosis is hindered by variable symptoms and inconsistent imaging results, including normal brain MRI and unreliable spinal opening pressures.

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A change of orbital state alters the coupling between ions and their surroundings drastically. Orbital excitations are hence key to understand and control interaction of ions. Rare-earth elements with strong magneto-crystalline anisotropy (MCA) are important ingredients for magnetic devices.

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CSF-venous fistulas (CVFs), which are an increasingly recognized cause of spontaneous intracranial hypotension (SIH), are often diminutive in size and exceedingly difficult to detect by conventional imaging. This purpose of this study was to compare energy-integrating detector (EID) CT myelography and photon-counting detector (PCD) CT myelography in terms of image quality and diagnostic performance for detecting CVFs in patients with SIH. This retrospective study included 38 patients (15 men and 23 women; mean age, 55 ± 10 [SD] years) with SIH who underwent both clinically indicated EID CT myelography (slice thickness, 0.

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Spontaneous intracranial hypotension (SIH) is a treatable cause of orthostatic headaches secondary to pathologic loss of cerebrospinal fluid (CSF) from the subarachnoid space. SIH has several known pathologic causes including dural tears from disc osteophytes, leaks emanating from nerve root sleeve diverticula, and CSF-venous fistulas (CVFs). Depending on the type of leak, surgical repair or endovascular techniques may be options for definite treatment.

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Background & Objectives: Spontaneous intracranial hypotension (SIH) is an underdiagnosed and debilitating condition caused by a spinal cerebrospinal fluid (CSF) leak. Although SIH can lead to substantial morbidity and disability, little data exists about patients' perspectives. Without hearing directly from patients, our understanding of the full experience of having SIH is limited, as is our ability to identify and use appropriate patient-reported outcome measures (PROMs) within clinical care and research.

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Background And Purpose: The Bern score is a quantitative scale characterizing brain MR imaging changes in spontaneous intracranial hypotension. Higher scores are associated with more abnormalities on brain MR imaging, raising the question of whether the score can serve as a measure of disease severity. However, the relationship between clinical symptom severity and the Bern score has not been evaluated.

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Background And Purpose: CSF-venous fistulas are an important cause of spontaneous intracranial hypotension but are challenging to detect. A newly described technique known as resisted inspiration has been found to augment the CSF-venous pressure gradient and was hypothesized to be of potential use in CSF-venous fistula detection but has not yet been investigated in patients with spontaneous intracranial hypotension. The purpose of this investigation was to determine whether resisted inspiration results in improved visibility of CSF-venous fistulas on CT myelography in patients with spontaneous intracranial hypotension.

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CSF-venous fistulas are an increasingly recognized type of CSF leak that can be particularly challenging to detect, even with recently improved imaging techniques. Currently, most institutions use decubitus digital subtraction myelography or dynamic CT myelography to localize CSF-venous fistulas. Photon-counting detector CT is a relatively recent advancement that has many theoretical benefits, including excellent spatial resolution, high temporal resolution, and spectral imaging capabilities.

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Background: Spontaneous intracranial hypotension is an important cause of treatable secondary headaches. Evidence on the efficacy of epidural blood patching and surgery for spontaneous intracranial hypotension has not been synthesized.

Purpose: Our aim was to identify evidence clusters and knowledge gaps in the efficacy of treatments for spontaneous intracranial hypotension to prioritize future research.

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Artificial intelligence (AI) application development is underway in all areas of radiology where many promising tools are focused on the spine and spinal cord. In the past decade, multiple spine AI algorithms have been created based on radiographs, computed tomography, and magnetic resonance imaging. These algorithms have wide-ranging purposes including automatic labeling of vertebral levels, automated description of disc degenerative changes, detection and classification of spine trauma, identification of osseous lesions, and the assessment of cord pathology.

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Article Synopsis
  • A growing variety of image-guided spine interventions are offering quick and effective pain relief, but the rapid introduction of these new techniques often outpaces the research that supports their efficacy.
  • The article discusses controversies surrounding four types of interventions—postdural puncture headache treatments, epidural steroid injections for nerve pain, facet and sacroiliac joint pain interventions, and vertebral augmentations for fractures—highlighting the mixed acceptance of clinical trial results due to differing methodologies.
  • Despite ongoing debates over these treatments, there is optimism for the development of effective solutions that could help alleviate various debilitating spinal conditions.
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Facet joint (FJ) disease is a common cause of axial low back pain with many minimally invasive image-guided treatment options. This article discusses fluoroscopic and CT-guided intraarticular FJ injections, medial branch (MB) radiofrequency ablation (RFA), and lumbar facet synovial cyst (LFSC) aspiration, rupture, or fenestration. Additionally, the article will highlight medial branch blocks (MBBs) utilized to diagnose facet-mediated pain and to predict outcomes to RFA.

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Study Design: Retrospective cohort study.

Objective: We aimed to characterize the treatment patterns and the associated costs in patients with cerebrospinal fluid (CSF) leak after spine procedures in the United States.

Background: CSF leak is a common complication after spinal procedures.

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Background: Spontaneous intracranial hypotension (SIH) is a debilitating disorder caused by non-iatrogenic spinal cerebrospinal fluid leaks. SIH is increasingly recognized as an important treatable cause of secondary headaches. Treatment involves either epidural blood patching or surgery, which have considerable differences in their adverse event rates, recovery times, and cost.

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Spontaneous intracranial hypotension (SIH) is a debilitating condition caused by spinal CSF leaks or CSF-venous fistulas (CVFs). Localizing the causative CSF leak or CVF is critical for definitive treatment but can be difficult using conventional myelographic techniques because these lesions are often low contrast compared to background, diminutive, and in some cases may be mistaken for calcified structures. Dual energy CT (DECT) can increase the conspicuity of iodinated contrast compared to background and can provide the ability to distinguish materials based on differing anatomic properties, making it well suited to address the shortcomings of conventional myelography in SIH.

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