Sharing Mono-Institutional Experience of Treating Pancreatic Cancer with Stereotactic Body Radiation Therapy (SBRT).

Background: Stereotactic body radiotherapy (SBRT) is an evolving treatment for the local management of pancreatic cancer (PC). The main purpose of this study is to report our initial experience in terms of local control (LC) and toxicity for PC patients treated with SBRT.

Methods: We conducted a retrospective review of patients treated with SBRT using abdominal compression (AC) or an end-expiratory breath-holding (EEBH) technique.

Comparison of Three Commercial Methods of Cone-Beam Computed Tomography-Based Dosimetric Analysis of Head-and-Neck Patients with Weight Loss.

Purpose: This investigation compares three commercial methods of cone-beam computed tomography (CBCT)-based dosimetric analysis to a method based on repeat computed tomography (CT).

Materials And Methods: Seventeen head-and-neck patients treated in 2020, and with a repeat CT, were included in the analyses. The planning CT was deformed to anatomy in repeat CT to generate a reference plan.

Dosimetric predictors of toxicity in a randomized study of short-course vs conventional radiotherapy for glioblastoma.

Purpose: There is no consensus on appropriate organ at risk (OAR) constraints for short-course radiotherapy for patients with glioblastoma. Using dosimetry and prospectively-collected toxicity data from a trial of short-course radiotherapy for glioblastoma, this study aims to empirically examine the OAR constraints, with particular attention to left hippocampus dosimetry and impact on neuro-cognitive decline.

Methods And Materials: Data was taken from a randomized control trial of 133 adults (age 18-70 years; ECOG performance score 0-2) with newly diagnosed glioblastoma treated with 60 Gy in 30 (conventional arm) versus 20 (short-course arm) fractions of adjuvant chemoradiotherapy (ClinicalTrials.

Brachytherapy workflow for locally advanced cervical cancer: A survey of Canadian Medical Physicists.

Purpose: To report on brachytherapy (BT) workflows for image-based treatments of locally advanced cervical cancer (CC) in Canada.

Methods: Medical Physicists in every Canadian cancer center were contacted and those with a CC-BT program were emailed a 44-item electronic questionnaire surveying workflow patterns including: fractionation schedules, prescription, equipment, imaging, and treatment delivery.

Results: Of 47 centers contacted, all 34 who performed CC-BT participated in the survey.

Prior data assisted compressed sensing: a novel MR imaging strategy for real time tracking of lung tumors.

Purpose: Hybrid radiotherapy-MRI devices promise real time tracking of moving tumors to focus the radiation portals to the tumor during irradiation. This approach will benefit from the increased temporal resolution of MRI's data acquisition and reconstruction. In this work, the authors propose a novel spatial-temporal compressed sensing (CS) imaging strategy for the real time MRI--prior data assisted compressed sensing (PDACS), which aims to improve the image quality of the conventional CS without significantly increasing reconstruction times.