Publications by authors named "Amr E Fouly"
Micro RNA-34a-5p (miR-34a-5p) is an important molecule that can act as a modulator of tumor growth. It controls expression of a plenty of proteins controlling cell cycle, differentiation and apoptosis and opposing processes that favor viability of cancer cells, their metastasis and resistance to chemotherapy. Bioinformatics analysis indicated that minichromosome maintenance protein 2 (MCM2) is a target gene of miR-34a-p.
View Article and Find Full Text PDFUnlabelled: Radioembolization has been demonstrated to allow locoregional therapy of patients with hepatocellular carcinoma not eligible for transarterial chemoembolization or other local therapies. The aim of this study was to validate evidence of the safety and efficacy of this treatment in a European sample of patients with advanced hepatocellular carcinoma (HCC). Therefore, 108 consecutive patients with advanced HCC and liver cirrhosis were included.
View Article and Find Full Text PDFArticle Synopsis
- The study tested the effectiveness and safety of pegylated interferon alfa-2b for treating acute hepatitis C virus infections, as previous evaluations were lacking.
- A total of 175 patients were enrolled, with 129 starting treatment at different weeks (8, 12, or 20), and the main goal was to achieve undetectable HCV RNA 24 weeks after treatment.
- The results showed an overall sustained virologic response (SVR) rate of 87%, with higher success rates for earlier treatment initiation, particularly beneficial for certain genotypes of the virus.