An accelerated hypofractionated schedule with a daily concomitant boost after breast conservation surgery: the feasibility and toxicity.

Aims And Background: Reduction of overall treatment time of postoperative irradiation and evaluation of the feasibility and preliminary toxicity of an accelerated hypofractionated whole breast irradiation with an addition of a concomitant daily boost in patients with early breast cancer submitted to conservation surgery.

Materials: Between June 2010 and September 2011, 122 patients underwent accelerated hypofractionated adjuvant radiation after conservation surgery (pT1 or pT2, pN0-N1). Radiotherapy consisted of 45 Gy, to the whole breast in 20 fractions with 2.