Effect of physical exercise on bone density and remodeling in egyptian type 1 diabetic osteopenic adolescents.

Background: The study was planned to assess effect of physical exercise on bone remodeling in type I diabetics with osteopenia.

Methods: Twenty-four type I diabetes mellitus (DM1) with osteopenia (10 females and 14 males) were compared to thirty-eight age- and sex-matched healthy control individuals (20 females and 18 males) for biochemical and radiologic parameters of bone mass. Laboratory investigations included serum and urinary calcium, inorganic phosphorus, alkaline phosphatase, and serum "procollagen type 1 N-terminal propeptide (P1NP).