identification and expression analysis of breast cancer-related mA-SNPs.

Research on mA-associated SNPs (mA-SNPs) has emerged recently due to their possible critical roles in many key biological processes. In this sense, several investigations have identified mA-SNPs in different diseases. In order to gain a more complete understanding of the role that mA-SNPs can play in breast cancer, we performed an analysis to identify the mA-SNPs associated with breast cancer and to evaluate their possible effects.

Nomogram including the total tumoral load in the sentinel nodes assessed by one-step nucleic acid amplification as a new factor for predicting nonsentinel lymph node metastasis in breast cancer patients.

Several models have been developed to predict non-sentinel nodes (NSLN) metastasis in patients with a positive sentinel node (SLN) that incorporates a standard pathology examination of the SLN. It has been reported that total tumoral load (TTL) in the SLNs assessed by one-step nucleic acid amplification (OSNA) is a predictive factor for additional NSLN metastasis in the axillary lymph node dissection (ALND). The objective was to develop a nomogram that predicts patient´s risk of additional NSLN metastasis incorporating TTL in the SLNs assessed by OSNA.

[Penile metastasis like first sign of esophagus carcinoma].

We present a new case of penile metastatic disease. The original tumour has been situated in the esophagus, which is a rare clinical situation. But what becomes exceptional in our clinical case is that the penile metastasis was the first disease symptom, since until this moment the original tumour has been silent.

[Paratesticular fibrous pseudotumor].

Objective: Benign testicular proliferative processes are known by the name of pseudotumors, because currently they are not considered real neoplasias. The paratesticular fibrous pseudotumor (PFP) is a rare entity the definition and etiopathogenesis of which is under great confusion. It is a process that misleads the clinical because they simulate neoplasias.