Publications by authors named "Amparo Benedicto-Buendia"
Article Synopsis
- Allergic diseases are immunological disorders triggered by allergens, leading to type 2 immunity and IgE responses, with a rising prevalence similar to cardiovascular diseases (CVD).
- CVD often stems from atherosclerosis, characterized by endothelial dysfunction and Th1 inflammation, raising questions about the relationship between allergic conditions and heart health.
- The review explores the phases of allergic pathology, immunological mechanisms of atherosclerosis, and the complex clinical connections between allergic diseases (like asthma and food allergies) and CVD, including the role of various immune cells and mediators in these conditions.
Introduction And Objectives: Many patients with nonvalvular atrial fibrillation are still left without protection due to a contraindication for anticoagulants. This study aimed to establish the occurrence of stroke and major bleeding events in patients with nonvalvular atrial fibrillation and left atrial appendage closure with long-term follow-up and to explore the factors associated with higher long-term mortality.
Methods: Analysis of a multicenter single cohort prospectively recruited from 2009 to 2015.
Aims: The aim of this study was to observe the percentage of thromboembolic and haemorrhagic events over a 2-year follow-up in patients with non-valvular atrial fibrillation (NVAF) undergoing closure of the left atrial appendage (LAA) with an occlusion device. Observed events and CHADS2 (congestive heart failure, hypertension, age, diabetes, stroke history), CHA2DS2-VASc (also adding: vascular disease and sex) and HAS-BLED (hypertension, abnormal liver/renal function, stroke history, bleeding predisposition, labile international normalised ratios, elderly, drugs/alcohol use)-predicted events were compared.
Methods: LAA closure with an occlusion device was performed in 167 NVAF patients contraindicated for oral anticoagulants and recruited from 12 hospitals between 2009 and 2013.