Naloxone decreases the inhibitory effect of alprazolam on the release of adrenocorticotropin/cortisol induced by physical exercise in man.

What Is Already Known About This Subject: • Alprazolam (ALP), a benzodiazepine activating GABAergic receptors, is involved in ACTH secretion.

What This Study Adds: • This study demonstrates a partial opioid influence in the inhibitory effect of ALP on the release of ACTH/cortisol during physical exercise.

Aims: To establish the possible involvement of alprazolam (ALP) and/or opiates in the mechanism underlying the ACTH/cortisol response to physical exercise.

Effects of moderate ethanol drinking on the GH and cortisol responses to physical exercise.

Objective: To evaluate the effects of moderate amounts of ethanol on the GH and cortisol responses to physical exercise.

Methods: Ten normal men underwent three bicycle ergometer tests. Test were carried out in basal conditions (control test) or after drinking 0.

Adrenocorticotropic hormone/cortisol response to physical exercise in abstinent alcoholic patients.

Background: Alterations in the hypothalamic-pituitary-adrenal (HPA) axis in alcoholic patients have been reported in various experimental conditions.

Methods: To establish whether alcoholism affects the HPA axis activation during physical exercise, 10 recent abstinent alcoholic patients (age range: 33-45 years; duration of alcohol dependence: range 4-6 years) were tested by exercising on a bicycle ergometer. Ten age-matched healthy nonalcoholic men participated as controls.

Different plasma neuropeptide Y concentrations in women athletes with and without menstrual cyclicity.

The circulating levels of leptin and neuropeptide Y, which are both involved in the control of feeding and reproduction, were measured in amenorrheic and normal cycling highly trained women athletes, and in normal cycling sedentary controls. Leptin showed similar low values in all athletes, whereas neuropeptide Y levels were significantly higher in normal cycling athletes than in the other groups, suggesting the possibility of a protective role of neuropeptide Y in the maintenance of the menstrual cycle in highly trained athletes.