Publications by authors named "Amol S Warokar"
Extraction, Isolation, Characterization, and Development of Phospholipids Complex Nanocarrier for Improved Solubility, Antiasthmatic, and Pharmacokinetic Potential of Curcuminoids.
Darshan R Telange Pragati V Pandhare Krutika R Sawarkar Ujwala N Mahajan Saurabh B Ganorkar Amol S Warokar
Curr Pharm Biotechnol
October 2024
Article Synopsis
- - The study focused on Curcuma longa (turmeric), known for its medicinal benefits but limited clinical use due to low oral bioavailability caused by its poor water solubility and rapid metabolism.
- - Researchers developed a complex called Phospholipon®90H-curcuminoid complex (CPLC) to enhance the solubility, antiasthmatic effects, and overall pharmacokinetic profile of curcuminoids by using a synthesis technique that involved solvent evaporation.
- - The findings showed that the CPLC significantly increased the aqueous solubility of curcuminoids, improved their bioavailability, and effectively reduced certain immune cell counts, suggesting its potential as a novel delivery system for curcumin in respiratory therapies
Randia dumetorum (RD) fruits in different form have been ethnopharmacologically reported to possess antiasthmatic property. Therefore, present study was undertaken to evaluate two different extracts of RD i.e.
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