Bilateral Central Retinal Vein Occlusion Associated with Axitinib Therapy: A Case Report.

Purpose: To describe a case of retinal vascular occlusion and cerebrovascular accident following axitinib therapy.

Methods: A retrospective chart review.

Result: A 65-year-old gentleman with a history of renal cell carcinoma and subsequent metastases to the brain was on axitinib at an oral daily dose of 10 mg.

Giant Perivascular Epithelioid Cell Tumor of the Orbit: A Clinicopathological Analysis and Review of the Literature.

Aim: To describe and review the clinical, radiological, and histopathological characteristics of an orbital perivascular epithelioid cell tumor (PEComa).

Methods: A systematic review of clinical records, radiological investigations, microscopic features, and immunohistochemical characteristics was done.

Results: A 9-year-old female child presented with a year-long history of a large orbital mass associated with painless, progressive proptosis of the right eye.

Nontraumatic subperiosteal orbital hemorrhage following upper gastrointestinal endoscopy.

Subperiosteal hemorrhages are typically the result of blunt orbital or facial trauma. Nontraumatic subperiosteal hemorrhages are uncommon and are usually attributed to increase in central venous pressure and bleeding disorders. Here, we report the case of a 38-year-old female who underwent an upper gastrointestinal (GI) endoscopy and developed bilateral nontraumatic subperiosteal hemorrhages that resolved with conservative treatment.

Actinomycetes canaliculitis complicating congenital nasolacrimal duct obstruction in an infant.

Actinomyces israelii is a Gram-positive anaerobic organism commonly associated with canaliculitis in adults. Pediatric canaliculitis is relatively rare, especially in infancy. We report the case of an 11-month-old boy who presented with co-existing canaliculitis and congenital nasolacrimal obstruction.