Publications by authors named "Amna R Soomro"
Background And Objective: Diagnosis of esophageal diseases is often hampered by sampling errors that are inherent in endoscopic biopsy, the standard of care. Spectrally encoded confocal microscopy (SECM) is a high-speed reflectance confocal endomicroscopy technology that has the potential to visualize cellular features from large regions of the esophagus, greatly decreasing the likelihood of sampling error. In this paper, we report results from a pilot clinical study imaging the human esophagus in vivo with a prototype SECM endoscopic probe.
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- Study aimed to assess the safety and feasibility of a new biopsy guidance method using volumetric laser endomicroscopy (VLE) for patients with Barrett's esophagus.
- The study involved 22 participants at Massachusetts General Hospital, with real-time marking of biopsy sites in 10 participants, showing no adverse events and effective visibility of laser marks.
- Results indicated high accuracy in diagnosing tissue near the marks, with VLE achieving 93%-100% accuracy compared to traditional methods, although findings are based on a single-center approach and a small sample size.