Development of DNA Markers for Acute Hepatopancreatic Necrosis Disease Tolerance in through a Genome-Wide Association Study.

Shrimp aquaculture is facing a serious disease, acute hepatopancreatic necrosis disease (AHPND), caused by (Vp). For sustainable shrimp aquaculture, massive losses of shrimp infected with Vp must be prevented. Research and selection of shrimp tolerant to Vp infection is a sustainable approach to reducing the risk of AHPND.

Nucleus-forming vibriophage cocktail reduces shrimp mortality in the presence of pathogenic bacteria.

The global aquaculture industry has suffered significant losses due to the outbreak of Acute Hepatopancreatic Necrosis Disease (AHPND) caused by Vibrio parahaemolyticus. Since the use of antibiotics as control agents has not been shown to be effective, an alternative anti-infective regimen, such as phage therapy, has been proposed. Here, we employed high-throughput screening for potential phages from 98 seawater samples and obtained 14 phages exhibiting diverse host specificity patterns against pathogenic VP strains.