Publications by authors named "Ammar Aldabbagh"
Article Synopsis
- Pregnancy-related liver diseases significantly contribute to maternal and fetal health issues, with preeclampsia being the most common, followed by hyperemesis gravidarum.
- The study analyzed data from 112 patients to understand demographic factors, gestational age at diagnosis, and outcomes, revealing that younger patients were more likely to experience hyperemesis gravidarum.
- Fetal complications occurred in 26% of cases, highlighting the serious implications these liver diseases have on both maternal and fetal well-being.
Article Synopsis
- Pregnancy-associated hemolytic uremic syndrome (P-aHUS) is a serious condition that poses a high risk of mortality and can lead to end-stage renal disease in over 50% of untreated patients, often presenting postpartum.
- The syndrome is linked to a disruption in the complement alternative pathway, causing damage to blood vessel linings and mimicking other postpartum conditions like severe pre-eclampsia and thrombotic microangiopathy.
- Diagnosis may involve genetic testing and assessment for anti-CFH antibodies, but supportive care and plasmapheresis are crucial, with eculizumab recommended for effective treatment from the point of diagnosis.
Background: Laparoscopic sleeve gastrectomy (LSG) is the most commonly performed surgery to treat morbid obesity. Post-LSG leak and stenosis are serious complications that can be associated with significant morbidity and mortality.
Objective: The objective was to report the efficacy and safety profile of using specifically designed fully covered self-expandable metallic stent for the treatment of post-LSG complications.
Background: Nonalcoholic fatty liver disease (NAFLD) is a common cause of chronic liver disease (CLD). NAFLD is also related to obesity and metabolic syndromes, which are common in Saudi Arabia. However, it is yet unclear what proportion of CLD cases is because of NAFLD in Saudi Arabia.
View Article and Find Full Text PDFPregnancy-associated atypical hemolytic uremic syndrome (P-aHUS) is a rare condition. It is characterized by very high maternal mortality and morbidity. Most cases of P-aHUS (79%) manifest in the postpartum period; this is probably due to the complement's involvement in aHUS pathogenesis.
View Article and Find Full Text PDFTo delineate the clinical features and outcomes of dengue infection and to guide clinician of early diagnosis and identification of risks factors for dengue hemorrhagic fever. Methods: This study is a retrospective cross-sectional. Clinical records of 567 patients with a confirmed diagnosis of dengue infection, admitted to a single hospital in Jeddah, Saudi Arabia, between January 2010 and June 2014 were reviewed.
View Article and Find Full Text PDFArticle Synopsis
- LuxI is crucial for bioluminescence in Vibrio fischeri and is part of the quorum sensing pathway, which involves signal molecule synthesis.
- Researchers used homology modeling to create and refine five models of LuxI, with Model 4 showing the highest quality and reliability.
- The study identified ten experimental compounds from DrugBank that could effectively bind to LuxI's active site, indicating potential for developing new antimicrobials.