Publications by authors named "Amma A Benneh"

Objective: To determine the occurrence of and risk factors for fetomaternal hemorrhage (FMH) among pregnant women at Korle Bu Teaching Hospital in Accra, Ghana.

Methods: A prospective study of FMH among pregnant women without hemoglobinopathies in the second trimester attending prenatal care between October 2015 and May 2016 performed using the Kleihauer-Betke test. Volume of FMH was estimated; ABO and Rh blood groups of participants were determined.

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Article Synopsis
  • FISH is a technique that quickly identifies genetic abnormalities, but such facilities are scarce in Ghana and nearby countries.
  • This study explores using interphase FISH on archival methanol-fixed samples for diagnosing chronic myeloid leukemia (CML) in a more equipped facility.
  • Results showed that 95% of the CML bone marrow samples tested positive for a specific genetic marker (BCR-ABL), demonstrating that older samples can still be effectively used for diagnosis.
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Introduction: Sickle cell disease is a collection of autosomal recessive genetic disorders. It includes homozygous HbSS and double heterozygote combinations such as HbSC. Central and West Africa bears a significant burden of HbSC disease.

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Patients with neurofibromatosis type 1 (NF1), a common, progressive, autosomal dominant neurocutaneous disorder, are predisposed to malignancies. Several types of hematologic malignancies have been described in them. However, to date there has been no report to the best of our knowledge of a patient with NF1 developing chronic myeloid leukemia (CML).

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