Publications by authors named "Amjad A Alharbi"
Article Synopsis
- This research investigates the potential link between proton pump inhibitors (PPIs) and rhabdomyolysis using data from the FDA's Adverse Event Reporting System (FAERS) from 2013 to 2021.
- Out of nearly 8 million reports, 57 cases were found connecting PPIs to rhabdomyolysis, with significant associations detected in both users and non-users of statins, though the strength of the association varied.
- The study concludes that while there are significant signals linking PPIs to rhabdomyolysis, these signals are more pronounced in reports that did not involve statin use compared to those that did.
β-thalassemia is characterized by the faulty generation of hemoglobin resulting in an elevated α/β globin ratio; this led to several patients needing red blood cell (RBC) transfusions for the rest of their lives. Luspatercept is an erythroid maturation test for treating various types of anemia, including β-thalassemia. It inhibits the Smad2/3 cascade and treats β-thalassemia by downregulating the transforming growth factor-beta (TGF-β) pathway.
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