Like rest of the world, the South Asian region is facing enormous challenges with the coronavirus disease 2019 (COVID-19) pandemic. The socioeconomic context of the eight South Asian countries is averse to any long-term lockdown program, but the region still observed stringent lockdown close to two months. This paper analyzed major measures in public health preparedness and responses in those countries in the pandemic.
View Article and Find Full Text PDFSurgical intervention results in a wound. In practice of surgery, wounds and their management is a fundamental job. Various surgical wounds are created by surgeons including abdominal laparotomy wounds.
View Article and Find Full Text PDFα-Crystallin is a multimeric protein belonging to the family of small heat shock proteins, which function as molecular chaperones by resisting heat and oxidative stress induced aggregation of other proteins. We immobilized α-Crystallin on a self-assembled monolayer on glass surface and studied its activity in terms of the prevention of aggregation of aldolase. We discovered that playing with grafted protein density led to interesting variations in the chaperone activity of immobilized α-Crystallin.
View Article and Find Full Text PDFAims: The aim of the study was to evaluate the difference in sodium, potassium, total protein in whole saliva in diabetic smokers, diabetic nonsmokers and healthy controls.
Materials And Methods: Nonstimulated saliva samples were collected from a group of diabetic smokers, diabetic nonsmokers, and controls. Supernatant after centrifugation was used to determine the levels of sodium, potassium, and total protein by using semiautomatic analyzer.
Aim: To assess the cases of ameloblastoma retrospectively for various parameters.
Materials And Methods: Ninety-one previously reported cases of ameloblastoma from Government Dental College and Hospitals, Nagpur, were included in this study. Data were collected considering parameters such as age, sex, symptoms, radiographic, histopathology, treatment modalities, and recurrence.
J Nat Sci Biol Med
January 2013
Background: Ameloblastoma is a rare, benign tumor of odontogenic epithelium, but with an aggressive clinical behavior.
Aim: The present study aims to assess the ultramicroscopic features of the epithelial and connective tissue components of ameloblastoma.
Materials And Methods: Six cases of ameloblastoma were subjected to electron microscopy.
Non-Hodgkin's lymphoma (NHL) is seldom seen in the oral cavity, and has been reported with some frequency in HIV-positive patients. Oral HIV-related lymphomas exhibit an aggressive course and can mimic other oral tumors and infections that make early recognition and diagnosis difficult. This paper presents a case of NHL on the gingiva of a 28-year-old HIV-positive male patient.
View Article and Find Full Text PDFThe direct formation of graphene on various dielectric surfaces is successful via a single-step rapid thermal processing (RTP) of substrates coated with amorphous carbon (C) and nickel (Ni) thin films. High-quality graphene is obtained uniformly on the whole surface of wafers with a controlled number of graphene layers. The monolayer graphene exhibits a low sheet resistance and a high optical transmittance in the visible range.
View Article and Find Full Text PDFAn efficient catalytic amination of aryl-substituted allylic alcohols has been developed. The complex [(η(3)-allyl)PdCl](2) modified by a bis phosphine ligand, L, has been used as catalyst in the reaction that afforded a wide range of allyl amines in good to excellent yield under mild conditions.
View Article and Find Full Text PDFA cross-metathesis reaction between an alkene terminated self-assembled monolayer (SAM) on glass/Si wafer and an alkene tethered Fischer carbene complex yielded a functionalized surface. Rapid aminolysis of the Fischer carbene moieties permit efficient anchoring of amine containing molecules on such a surface. Attachment of 1-pyrenemethylamine was thus monitored by ATR-IR spectroscopy and fluorescence microscopy.
View Article and Find Full Text PDFA Fischer carbene complex was grafted onto self-assembled monolayers (SAMs) on gold or glass by a copper-free "click" reaction. Pendant lysine residues of protein A obtained from Staphylococcus aureus rapidly reacted with the electrophilic metal complex on SAM effecting a covalent attachment of protein A with the surface. The protein A coated surface further led to bioaffinity immobilization of rabbit IgG in an oriented manner, a feature that also permits its purification from rabbit serum.
View Article and Find Full Text PDFAttachment of biomolecules on gold, silicon or glass surfaces has direct implications for the development of novel biosensors in the context of nanoscale detection of pathogens and other metabolites related to issues of human health. In this critical review, we have highlighted the current developments in various techniques of immobilization of biomolecules, specifically biological macromolecules on surfaces through the modification of a functional self-assembled monolayer. The utility of such immobilized biomolecules in the area of biosensing in nanoscale has been surveyed.
View Article and Find Full Text PDFA cross-coupling reaction of a variety of aryl, heteroaryl, and benzyl chlorides with ArMgX is catalyzed by 2 mol % of a nickel-phosphine complex prepared in situ from an equimolar amount of Ni(CH(3)CN)(2)Cl(2) and ligand (L2) to yield products in excellent yield in THF at room temperature. This new bidentate ligand (L2) is stable in air and forms a stable complex upon reaction with Ni(CH(3)CN)(2)Cl(2). Structures of the ligand and the complex were confirmed by single-crystal X-ray diffraction.
View Article and Find Full Text PDFA novel, air-stable phosphine ligand, prepared from readily available 2-bromonitrobenzene and vinylmagnesium bromide, combines with Pd(CH(3)CN)(2)Cl(2) to afford an effective catalyst for Suzuki-Miyaura cross-coupling of aryl, heteroaryl, and allyl chlorides with phenylboronic acid.
View Article and Find Full Text PDFAn efficient Hiyama coupling reaction between benzylic halide and aryltrialkoxysilane using Pd nanoparticles has been developed. This procedure accommodates various functional groups to yield a diverse range of diarylmethanes which are ubiquitous units of natural products and pharmaceuticals.
View Article and Find Full Text PDFFischer carbene complex anchored on glass or silicon surface using a Cu-free 'click' reaction allows facile and swift covalent grafting of protein molecules like Bovine Serum Albumin (BSA).
View Article and Find Full Text PDFAn efficient synthesis of Pd nanoparticles in water has been developed using a Fischer carbene complex of tungsten as the reductant and PEG as the capping agent. The colloidal palladium (1 mol %) efficiently catalyzes Hiyama cross-coupling reactions performed in air. Excellent yields of products were obtained with a wide range of substrates.
View Article and Find Full Text PDFSuitably designed, hydrophilic Fischer carbene complexes reduce HAuCl4 to produce stable gold nanoparticles localized on proteins in aqueous buffer solution.
View Article and Find Full Text PDFHepatitis B, is one of the major public health problems can be controlled with the active participation of the community. A descriptive cross-sectional study was conducted in the immunization clinic of Burdwan Medical College to identify the level of people's perception on the diseases Hepatitis B. A total of 210 individuals accompanying the children for routine immunization were interviewed.
View Article and Find Full Text PDFOne or more methoxy groups on the benzylic carbon at the ortho-position of tricarbonylchromium-complexed aryl aldehydes (2, 3 or 4) permit chelation-controlled addition of nucleophiles to the carbonyl function in the presence of Lewis acids. In the absence of a Lewis acid additive, a complementary set of diastereomeric products are obtained.
View Article and Find Full Text PDFA variety of groups like a Fischer carbene complex, an N-hydroxysuccinimide or a ferrocene derivative have been grafted by ruthenium-catalyzed cross-metathesis reaction with terminal alkene groups on monolayer-protected gold clusters as a mild and convenient strategy to anchor functional molecules.
View Article and Find Full Text PDFFormation of distinctly different products from the same alkoxide intermediate indicates a strong dependence of reaction pathways on counterions.
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