Medical Students' Perception of the Usage of Lecture Recording Software.

Background: Lecture recording software is a useful reference tool that allows students to revisit lectures and understand complicated concepts in higher education. It is also a useful tool for students with learning difficulties, allowing them to reference and learn the material at their own pace. A significant advantage of this tool is the accessibility of course material to the students off campus.

Oncocytic lesion of parotid gland: A dilemma for cytopathologists.

Oncocytes are epithelial cells with abundant, granular, eosinophilic cytoplasm due to presence of numerous large mitochondria of varied sizes. The presence of oncocytes in salivary glands can occur in a variety of conditions. Here, we present a rare case of a 68 year old male patient who presented with a 6 cm diameter swelling in the right parotid region.

Use and validation of epithelial recognition and fields of view algorithms on virtual slides to guide TMA construction.

While tissue microarrays (TMAs) are a form of high-throughput screening, they presently still require manual construction and interpretation. Because of predicted increasing demand for TMAs, we investigated whether their construction could be automated. We created both epithelial recognition algorithms (ERAs) and field of view (FOV) algorithms that could analyze virtual slides and select the areas of highest cancer cell density in the tissue block for coring (algorithmic TMA) and compared these to the cores manually selected (manual TMA) from the same tissue blocks.

Semi-automated imaging system to quantitate Her-2/neu membrane receptor immunoreactivity in human breast cancer.

Background: Immunocytochemical methods for quantitating Her-2/neu immunoreactivity rest on subjective semi-quantitative interpretations with resulting interobserver, intraobserver, and fatigue variability.

Methods: To standardize and quantitate measurements of Her-2/neu immunoreactivity, we created epithelial-recognition and specific membrane-recognition algorithms, which could image breast cancer cells against a background of stroma, compartmentalize the cancer cell into nucleus, cytoplasm and membrane, and quantitate the degree of Her-2/neu membrane immunoreactivity based on both gray scale intensity and RGB colorimetric determinations. Image acquisition utilized either scanner or microscope with attached camera with a resolution of 20 pixels/10 microm.

Solid and cystic tumor arising from an extrapancreatic site--a case report.

A case of solid and cystic tumor arising in the lesser Omentum of a 53 year old woman is presented. A well defined, encapsulated tumor measuring 7.5 x 6.

Altitude and growth among the sherpas of the eastern Himalayas.

The results of the anthropometric survey of Sherpa children of both sexes (n = 478) from high- and low-altitude areas in the eastern Himalayas are presented. The study reveals that growth is slower both more prolonged in the high-altitude Sherpas compared with growth at low altitude and that Sherpa children are the smallest of all the high-altitude populations considered here. Sexual dimorphism is not well defined during the earlier age periods.