Publications by authors named "Amit Wasti"

Introduction: Complete demineralization of hard tissues with preservation of organic components to retain their tissue architecture and to obtain thin section for histological examination is done by a process known as "decalcification". Tooth decalcification may be achieved by subjecting the tissue to a decalcifying chemical agent and employing heat, vacuum, or electric current to enhance the procedure. Completion of decalcification is adjudged by determination of end-point.

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Article Synopsis
  • Genomic methylation shows promise as a tool for identifying oral potentially malignant disorders (OPMDS) and oral cancer, which could enhance understanding of cancer mechanisms and lead to new therapies.
  • A study involving 112 patients with premalignant and malignant oral lesions analyzed saliva samples to investigate genetic markers like p16, DAP-K, and MGMT using advanced DNA methylation technology.
  • Findings indicated that 12.7% of oral cancer lesions displayed methylation of the examined genes, with higher rates of co-methylation, suggesting these genetic markers can aid in predicting the progression of oral cancer and patient outcomes.
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Background And Aim: Increased oxidative stress has emerged as one of the prime factors in the pathogenesis of periodontitis. Hence, antioxidant therapy may become a promising tool in the treatment of periodontal disease. Uric acid is a major salivary antioxidant, levels of which decrease in periodontitis.

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Aims And Objectives: The aim and objective of the present study was to explore the use of salivary calcium levels as a diagnostic biochemical marker for osteoporosis in menopausal women and also to find the correlation among oestrogen level, bone density and salivary calcium level.

Materials And Methods: The study included 180 individuals and they were divided into three groups with 60 individuals in each group, comprised of healthy women, pregnant women and post-menopausal women. All the women were asked to collect at least 2 ml of unstimulated whole saliva in the sterile plastic sample containers.

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