Publications by authors named "Amit S Pasari"
Article Synopsis
- * A case of a 54-year-old man with type 2 diabetes showed worsening pain in his calf, where tests confirmed muscle injury and inflammation as the cause of his symptoms.
- * Treatment included hemodialysis, medications for pain and blood sugar control, and lifestyle changes, highlighting the need for early diagnosis and management of DMI to prevent complications.
Article Synopsis
- * The patient's symptoms included swelling in lower limbs, facial puffiness, frothy urine, and difficulty breathing, with lab tests showing abnormal kidney function and imaging confirming infective endocarditis caused by Burkholderia cepacia and resistant Staphylococcus bacteria.
- * Multidisciplinary treatment involved respiratory support, hemodialysis, antibiotics, and blood transfusions, emphasizing the need for quick recognition and management of IRGN to prevent lasting kidney damage and other serious complications.
Article Synopsis
- Renal aspergillosis is a rare but serious complication following kidney transplants, highlighted by the case of a 45-year-old man who had a transplant from his mother.
- After initially recovering, the patient faced kidney dysfunction and signs of systemic infection due to active antibody-mediated rejection, leading to a diagnosis of renal aspergillosis.
- Despite aggressive treatment efforts, the patient's condition worsened to renal graft cortical necrosis, resulting in the need for nephrectomy, emphasizing the importance of early diagnosis and intervention in transplant patients.
Article Synopsis
- Maintenance hemodialysis (MHD) patients are at higher risk for severe COVID-19, and this study evaluated the antibody response to the COVISHIELD vaccine after two doses.
- Among 50 MHD patients, 96% showed seropositivity, with those having a prior COVID-19 infection exhibiting significantly higher antibody levels.
- The COVISHIELD vaccine proved to be effective and safe, with mild adverse events reported in one-third of patients but no serious complications.
Article Synopsis
- Kidney transplants are a key treatment for end-stage renal disease, but conditions like atypical hemolytic uremic syndrome (aHUS) can complicate outcomes and increase rejection risks.
- This case study discusses a young adult with aHUS who successfully received an ABO-incompatible kidney transplant, thanks to a method of desensitization that lowered the risk of rejection.
- The patient was given triple immunosuppressive therapy, and after four months, follow-up tests showed no signs of rejection or recurrence of aHUS, proving that ABO-incompatible transplants can be done safely in such patients.
Article Synopsis
- * A study analyzed 47 patients with aHUS, finding that 5 underwent kidney transplants, with most diagnosed before the procedure; only one had a recurrence post-transplant.
- * Pre-transplant treatments like plasma exchange and rituximab showed promise in minimizing disease severity and promoting good kidney function after transplant, with no reported recurrences during follow-up.
Background: Atypical hemolytic uremic syndrome (aHUS) is a rare disorder triggered by various stressors. Most of the time, stressors may not be identified in patients with aHUS. The disease may remain quiescent without manifestation throughout life.
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- Tacrolimus is a crucial medication for kidney transplant patients, with its metabolism influenced by genetic variations in the CYP3A5 gene.
- A study analyzed 25 kidney transplant patients based on their CYP3A5 genetic polymorphism status, classifying them into three groups: non-expressers, intermediate expressers, and expressers.
- The findings revealed that non-expressers required higher tacrolimus doses, experienced more complications like urinary tract infections and diabetes, and highlighted the importance of genetic testing for tailored medication plans.
Spectrum of Biopsy-proven Native Kidney Disease in Central India.
Saudi J Kidney Dis Transpl
September 2022
Article Synopsis
- - The study, conducted in Nagpur and Sawangi, India, analyzed 347 native kidney biopsies from January 2017 to March 2020, aiming to determine the prevalence of renal disorders and compare findings with previous studies.
- - The average age of patients undergoing biopsies was 41.41 years, with males making up 58.5%; nephrotic syndrome was the primary reason for biopsy (36.3%), followed by nephritic syndrome (19.9%).
- - The most common findings included primary glomerulopathies (69%), with IgA nephropathy being the most prevalent (30.85%), along with significant cases of membranous nephropathy and focal segmental glomer
Article Synopsis
- Tuberculosis (TB) can lead to a specific kidney condition called glomerulonephritis, which has symptoms like blood in urine, protein in urine, swelling, high blood pressure, or kidney failure, making it hard to differentiate from other kidney issues.
- Membranous nephropathy (MN), a type of kidney disease, is rare in TB patients.
- A case study highlights a 30-year-old woman with TB who developed MN after starting treatment for TB, which improved after she completed her anti-TB therapy.
C3 glomerulopathy is usually seen with the presence of C3 nephritic factor, homozygous or heterozygous mutations in the regulatory complement proteins factor H, factor I, or C3. We describe the presence of heterozygous laminin β2 mutation in a patient of C3 glomerulonephritis with ocular and central nervous system involvement, the significance of which is unknown.
View Article and Find Full Text PDFDiabetic muscle infarction is underdiagnosed complication occurring in dialysis patients with advanced diabetes mellitus. Atherosclerotic vascular disease and long-standing diabetes are risk factors for this painful condition. Most common presenting symptom is localized pain in the affected limb.
View Article and Find Full Text PDFIntroduction: Hemodialysis technicians play a crucial role in infection control practices in hemodialysis units. Thus, it is important to assess the knowledge and attitude towards COVID-19 among hemodialysis technicians in this pandemic situation.
Materials And Methods: An online survey composed of 22 closed-ended questions using Google Forms was conducted in the month of April (13th to 19th) 2020.