Synthesis and characterization of fullerene-based nanocarrier for targeted delivery of quercetin to the brain.

Preparation of quercetin fullerene conjugate (QFC) for nose-to-brain delivery and their and characterizations. Carboxylated fullerene was converted into acetylated fullerene and quercetin was conjugated and physically adsorbed on acetylated fullerene. The particle size and zeta potential of QFC and chitosan-coated QFC (CC-QFC) were found to be 179.