Synopsis of recent research by authors named "Amit Kumar Gaurav"
- Amit Kumar Gaurav's research primarily focuses on the molecular mechanisms underlying the biology of protozoan parasites, particularly in relation to telomere maintenance and gene expression regulation in Trypanosoma brucei, which is crucial for understanding its pathogenicity in human African trypanosomiasis.
- Key findings emphasize the role of the RAP1 protein in binding to DNA and regulating the monoallelic expression of the variant surface glycoprotein (VSG), highlighting its importance in host immune evasion strategies.
- Additionally, Gaurav's work explores the interaction and regulation of telomere repeat-containing RNA (TERRA) in cell cycle dynamics, as well as the role of cytosine DNA methylation in the transcriptional activity of retrotransposons in Entamoeba histolytica, revealing insights into epigenetic regulation in these organisms.
