Introduction: Obsessive-compulsive disorder (OCD) is characterized by underlying obsessions and yielding/nonyielding compulsions, which often leads to significant levels of distress for the individual. Recently, obsessive-compulsive symptoms have been grouped into various symptom dimensions. The Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS) gives a comprehensive picture regarding symptom severity in each individual dimension of OCD, while also providing a global severity score.
View Article and Find Full Text PDFIn this paper we write exactly solvable generalizations of one-dimensional quantum XY and Ising-like models by using 2^{d}-dimensional gamma matrices as the degrees of freedom on each site. We show that these models result in quadratic Fermionic Hamiltonians with Jordan-Wigner-like transformations. We illustrate the techniques using a specific case of four-dimensional gamma matrices and explore the quantum phase transitions present in the model.
View Article and Find Full Text PDFTo date, there is no satisfactory and effective therapy available to cure type 2 diabetes mellitus (T2DM). This present work is focused on plant extracts and the effect of saroglitazar and TET genes on oxidative stress and inflammation in vitro adipocytes. Aqueous extracts of and seed have shown potent antidiabetic activity that decreases glucose levels in diabetic adipocytes.
View Article and Find Full Text PDFDiverse complex dynamical systems are known to exhibit abrupt regime shifts at bifurcation points of the saddle-node type. The dynamics of most of these systems, however, have a stochastic component resulting in noise-driven regime shifts even if the system is away from the bifurcation points. In this paper, we propose a new quantitative measure, namely, the propensity transition point as an indicator of stochastic regime shifts.
View Article and Find Full Text PDFRecently, a large number of studies have been carried out on the early signatures of sudden regime shifts in systems as diverse as ecosystems, financial markets, population biology and complex diseases. The signatures of regime shifts in gene expression dynamics are less systematically investigated. In this paper, we consider sudden regime shifts in the gene expression dynamics described by a fold-bifurcation model involving bistability and hysteresis.
View Article and Find Full Text PDFWe study the entanglement properties of a molecular three-qubit system described by the Heisenberg spin Hamiltonian with anisotropic exchange interactions and including an external magnetic field. The system exhibits first-order quantum phase transitions by tuning two parameters, x and y, of the Hamiltonian to specific values. The three-qubit chain is open-ended so that there are two types of pairwise entanglement: nearest-neighbour (nn) and next-nearest-neighbour (nnn).
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