Publications by authors named "Amit K Janu"

Purpose: To evaluate the multimodality imaging features of chondroblastoma.

Materials And Methods: Retrospective analysis of imaging features of 52 cases of histopathologically proven chondroblastoma from 2010 to 2022 was performed. Radiographs were evaluated for lesion site, location, morphology, margins, matrix mineralization, cortical breach, periosteal reaction, eccentricity, and subarticular extension.

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Article Synopsis
  • * A dataset of 117 patients was analyzed, using convolutional neural network (CNN) architecture to assess the accuracy of various MRI sequences for classification while testing associations with factors like smoking history and performance status.
  • * Results indicated that the CNN model achieved 76% accuracy in classifying genetic mutations, while semantic analysis highlighted significant demographic trends related to mutation positivity, particularly noting differences in smoking status and lesion characteristics.
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Background: Treatment of malignant melanoma has undergone a paradigm shift with the advent of immune checkpoint inhibitors (ICI) and targeted therapies. However, access to ICI is limited in low-middle income countries (LMICs).

Patients And Methods: Histologically confirmed malignant melanoma cases registered from 2013 to 2019 were analysed for pattern of care, safety, and efficacy of systemic therapies (ST).

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Purpose: To evaluate safety and long-term efficacy of radiofrequency (RF) ablation in treatment of chondroblastoma.

Materials And Methods: This retrospective analysis comprised 27 consecutive patients with histopathologically proven chondroblastoma treated by RF ablation. The tumors were located in the proximal humerus (n = 6), proximal tibia (n = 8), proximal femur (n = 6), distal femur (n = 5), acromion process (n = 1), and lunate (n = 1).

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Background: This study aimed at evaluating the imaging findings of phosphaturic mesenchymal tumors and tumor-induced osteomalacia and assess the clinical and biochemical profiles of patients with tumor-induced osteomalacia.

Materials And Methods: Imaging findings in six patients with tumor-induced osteomalacia and histopathologically proven phosphaturic mesenchymal tumors were evaluated. Clinical and biochemical profiles of these patients were also assessed.

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