Publications by authors named "Amit Bhat"

Article Synopsis
  • The study aims to evaluate the effectiveness and safety of long-acting growth hormone (LAGH) therapies for treating growth hormone deficiency (GHD) in prepubertal children, reviewing studies published until July 2023.
  • PEG-LAGH was found to significantly outperform other LAGH options (like somatrogon and somapacitan) in height velocity and standard deviation scores, indicating it may be the best choice for improving growth in these children.
  • Additionally, PEG-LAGH demonstrated a comparable or lower risk of adverse effects compared to other LAGH therapies and daily growth hormone treatments, highlighting its safety as an effective option for growth hormone replacement.
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Objective: The Chinese healthcare industry has immense potential for innovation and requires competent publication professionals for global reach. Changes in regulatory landscape of China necessitates pharmaceutical industries to collaborate with medical professionals who are capable of keeping up with both changes in regulations and innovative medicine.

Methods: We initiated an online questionnaire-based survey WeChat from August 3 to August 14, 2019 which focused on experience level, challenges, career development, and training requirements of survey participants.

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Aim: Non-peer-reviewed manuscripts posted as preprints can be cited in peer-reviewed articles, which has both merits and demerits. International Committee of Medical Journal Editors guidelines mandate authors to declare preprints at the time of manuscript submission. We evaluated the trends in pharma-authored research published as preprints and their scientific and social media impact by analyzing citation rates and altmetrics.

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Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak is a serious health concern. Repurposing of existing drugs indicated for other conditions seems to be the first choice for immediate therapeutic management. The quality of early evidence favoring the different treatment options needs to be apprised for informed decision-making.

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The present retrospective, single-center study evaluated the objective response rate (ORR) and progression-free survival (PFS) of epidermal growth factor receptor (EGFR) mutation-positive Malaysian patients with advanced lung adenocarcinoma treated with gefitinib. During May 2008 to July 2013, 33 patients with Stage IV, EGFR mutation-positive non-small-cell lung cancer (NSCLC) were identified and received gefitinib (250 mg) as first line treatment. The primary and secondary end points were ORR, PFS and safety, respectively.

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Radical cystectomy has emerged as a standard treatment option for patients with muscle invasive bladder cancer. The impact of nerve-sparing cystectomy with urethra and vaginal sparing has not been quantified with validated questionnaires. We report our experience with nerve-sparing orthotopic radical cystectomy and the impact on postoperative sexual function.

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