[Reduction in the need for glucocorticoids on the background of therapy with biologic disease-modifying antirheumatic drugs and Janus kinase inhibitors in rheumatoid arthritis: evidence from real clinical practice].

Background: Clinical guidelines for the treatment of rheumatoid arthritis (RA) recommend reducing the use of glucocorticoids (GCs) due to the high risk of associated complications.

Aim: To determine the frequency of GC cancellations and dose reductions in real clinical practice, while taking into account active RA therapy.

Materials And Methods: The study group consisted of 303 patients with RA reliable according to ACR/EULAR criteria (women 79.

Are the Goals of Therapy Achievable in Patients with Rheumatoid Arthritis Receiving Upadacitinib in Real Clinical Practice?

The aim of the study was to evaluate the effectiveness of UPA in RA patients in real clinical practice after 3 and 6 months of therapy. The study included 63 RA patients with high activity of the disease. Activity was assessed according to the DAS28(ESR), DAS28(CRP), SDAI, CDAI; functional ability to HAQ; quality of life to the EQ-5D; disease activity according to the patient's RAPID-3 index; the level of depression and anxiety to the HADS scale.

Magnetic therapy in acute and subacute non-specific back pain: Results of an open multicenter study.

Magnetic therapy (MT) is a non-drug method that improves the effectiveness of treatment of musculoskeletal pain, including:acute non-specific back pain (NBP). Objective of our study was to evaluate the results of complex treatment of patients with acute/subacute NBP at home using MT. The study group consisted of 339 patients with severe acute/subacute NBP.

[Efficacy of combined use of glycosaminoglycan peptide complex for intramuscular administration and oral diacerein in osteoarthritis: evaluation according to an observational multicenter clinical trial].

Background: The combined use of intramuscular injection glycosaminoglycan peptide complex (GPC) and oral diacerein can increase the effectiveness of treatment of osteoarthritis (OA).

Aim: Compare the effectiveness of combination GPC + diacerein and GPC monotherapy in the treatment of OA in clinical practice.

Materials And Methods: A retrospective evaluation of the results of a 12-week multicenter observational non-interventional study of the effectiveness of GPC (Rumalon, a course of intramuscular injections 3 times a week, №25) in patients with moderate/severe OA (n=2955) requiring regular administration of nonsteroidal anti-inflammatory drugs (NSAIDs).

[Control of pain in the early post-traumatic period in the outpatient practice. Results of the multi-center observational study RAPTOR (Rational Analgesia PostTraumatic: an Observational Research)].

Aim: Evaluate the frequency, nature and course of PTP, as well as the effectiveness and safety of NSAIDs in PTP in real clinical practice.

Materials And Methods: The assessment of the condition and need for NSAIDs (original meloxicam) in 1115 outpatient patients who suffered a fracture of the radius (32.2%), injury to the knee (35.

[What factors affect the effectiveness of long - term analgesic therapy for osteoarthritis? Data analysis of the multi - center 3-month PARACELSUS study].

There are factors that can affect the effectiveness of treatment of osteoarthritis (OA). Aim to identify factors affecting the effectiveness of long - term analgesic therapy in OA. Materials and methods.

[The efficacy of meloxicam in acute back pain: results of an observational non-interventional multicenter study].

Aim: To evaluate the efficacy of non-steroidal anti-inflammatory drugs (NSAIDs) (meloxicam) in acute nonspecific back pain (NSBP) depending on influence of clinical and anamnestic factors.

Material And Methods: The studied group included 2078 patients presented with an acute NSBP. All study subjects received meloxicam in a dose of 15 mg/day: 86.

[Russian society and patients with rheumatic diseases].

The morbidity, primary morbidity, temporary incapacity for work and disablement due to rheumatoid diseases registered among Russia's population in the recent 3 years are described on the basis of an analysis of Russian statistics. Issues related with mortality, caused by rheumatic diseases, the related expenses and influence on patients' life quality are under discussion. A conclusion is made on a high social-and-medical importance of the above category of diseases as viewed from the standpoint of society (state), patient and his or her family.

[Incidence rate of rheumatic diseases in Russian population: 10-year analysis].

Aim: To analyze trends in rheumatic diseases (RD) incidence rate in population of Russia for a recent decade.

Material And Methods: Medical RD statistics for all regions of Russia for 10 years (1990-1999) have been analysed.

Results: Annual number of primary patients with RD has increased for 1990-1999 from 9,147,000 to 12,378,000 (by 35.

[Role of the Institute of Rheumatology in formation and development of State controlling system of rheumatic diseases].

The paper gives a brief account of the stages of formation and development of rheumatological care in the country, which are closely related to the researches and practical activities of the Institute of Rheumatology.

[Evaluation and prognosis of work capacity in rheumatoid arthritis].

Assessment of the functional state, social and psychological status of 82 patients with RA was made with the aid of a modified health assessment questionnaire (HAQ) and individual arthritis impact measurement scales (AIMS). A group of disabled persons exhibited a greater markedness of articular destruction, high activity of the disease and a high functional index, all of them being old persons. Patients with working ability underwent prophylactic medical examination, more intensive therapy with basic drugs.

[A study of the dynamics of a contingent of patients with rheumatic diseases during ambulatory care (based on data from polyclinics in Moscow and the Moscow region)].

The analysis of the contingent of patients with rheumatic diseases taken under dispensary observation (DO) in 1985-1986 (625 persons) showed that in many polyclinics of Moscow and the Moscow region there took place substantial changes in the contingent of these patients and extension of its scope at the expense of inclusion of all nosological forms corresponding to the Regulation of the USSR Ministry of Health. Yet untimely detection and prophylactic medical examination of a great number of patients with rheumatic diseases (RD) was noted. Patients with deforming osteoarthrosis were not given due consideration.

[The use of a modified Health Assessment Questionnaire for evaluating the effectiveness of therapy at a hospital].

A study was made of a possibility of estimating the efficacy of hospital therapy of patients suffering from rheumatoid arthritis (RA) using the modified Stanford health assessment questionnaire. The general functional index (GFI) derived on the basis of the questionnaire was found to be in good agreement with a number of the commonly accepted indicators in rheumatology: Richi's articular index, the swelling index, the power of pain in accordance with the visual analog scale, hand force as well as with the psychological and social characteristics. The GFI was shown to decrease significantly after the treatment carried out under hospital conditions together with a decrease of pain and the articular index (p less than 0.