Publications by authors named "Amira Samy Khedr"
Diabetes mellitus (DM) and premenstrual syndrome (PMS) are global health challenges. Both disorders are often linked to a range of physical and psychological symptoms that significantly impact the quality of life of many women. Yet, the exact relation between DM and PMS is not clear, and the management of both conditions poses a considerable challenge.
View Article and Find Full Text PDFA Systematic Review of Novel Therapies of Pulmonary Arterial Hypertension.
Am J Cardiovasc Drugs
January 2024
Article Synopsis
- - Pulmonary arterial hypertension (PAH) is a serious, progressive condition that causes increased pressure in the lungs, leading to heart failure, and researchers are exploring new treatments to alleviate symptoms and improve patient outcomes.
- - This systematic review analyzed 8 randomized controlled trials focusing on the effectiveness of various potential treatments, including Rho-kinase inhibitors, BMP2 inhibitors, estrogen inhibitors, and AMPK activators, but faced challenges in conducting a meta-analysis due to differences in study designs and outcome measures.
- - Key findings suggest that metformin and the BMP2 inhibitor sotatercept show promise for modifying PAH, while the effects of other drugs, such as fasudil and anastrozole, require further long-term study to