Publications by authors named "Amira Hannoun"
J Biosci Bioeng
January 2025
Article Synopsis
- The study aimed to create engineered cartilage using pyrocarbon (PyC) biomaterial and differentiated chondrocytes, focusing on a scaffold-free and mechanically stimulated process.
- By applying uniaxial cyclic compression in a specially designed tribo-bioreactor, the researchers aimed to keep the chondrocytes in a cartilage-like phenotype while enhancing the matrix composition.
- Findings indicated that the combination of PyC and dynamic stimulation led to denser constructs with improved mechanical properties and no signs of unwanted cell maturation, highlighting the effectiveness of integrating biomaterials with mechanical stimuli in tissue engineering.
