Synopsis of recent research by authors named "Amira Gepstein"
Amira Gepstein's research focuses on utilizing human-induced pluripotent stem cells (hiPSCs) to explore cardiac electrophysiology, particularly in relation to arrhythmias and therapeutic strategies.
She has developed innovative in vitro models to study the mechanisms of cardiac electroporation pulsed-field ablation (PFA), calcium handling disorders linked to RYR2 variants, and short/long QT syndromes through optogenetic approaches.
Gepstein's work emphasizes disease modeling, drug testing, and regenerative applications, aiming for advancements in personalized medicine for cardiovascular conditions.