Synopsis of recent research by authors named "Amira D Mahmoud"
- Amira D Mahmoud's recent research centers on the role of long non-coding RNAs (lncRNAs) and the AMP-activated protein kinase (AMPK) in cardiovascular function and respiratory control, specifically focusing on their impact on vascular smooth muscle cells and carotid body chemosensing.
- Key findings indicate that LKB1, a critical kinase for AMPK activation, plays a significant role in regulating carotid body responses during hypoxia and hypercapnia, while certain lncRNAs are implicated in pathological states and atherosclerosis progression.
- Her studies also explore the molecular mechanisms by which AMPK influences pulmonary vascular responses to hypoxia, contributing to the understanding of conditions like hypoxic pulmonary hypertension and providing insights for potential therapeutic targets.
