Publications by authors named "Amira Boukherissa"
Neurotropic pathogens, notably, herpesviruses, have been associated with significant neuropsychiatric effects. As a group, these pathogens can exploit molecular mimicry mechanisms to manipulate the host central nervous system to their advantage. Here, we present a systematic computational approach that may ultimately be used to unravel protein-protein interactions and molecular mimicry processes that have not yet been solved experimentally.
View Article and Find Full Text PDFHundreds of antimicrobial peptides create a selective barrier for insect gut symbionts.
Proc Natl Acad Sci U S A
June 2024
Article Synopsis
- The spatial structure of gut microbiota is vital for gut health, yet how these bacterial communities form in different areas remains unclear.
- In insects, the anterior midgut has a diverse bacterial community, while the posterior midgut mostly hosts a single bacterial type that withstands antimicrobial peptides (AMPs) produced in that region.
- Research identifies genetic pathways in these bacteria that help them resist AMPs, indicating that these defenses are essential for survival in the gut and may also play a role in interactions with the host.
This manuscript reports the complete and circularized Oxford Nanopore Technologies (ONT) long read-based genome sequences of five nitrogen-fixing symbionts belonging to the genus , isolated from root nodules of peanut () grown on soil samples collected from Tunisia.
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