Sequential peeling as a monotherapy for treatment of milder forms of acne vulgaris.

Background: Glycolic acid (GA) and salicylic acid (SA) peels have been used separately for acne treatment, not as a sequential peel.

Aim: To evaluate the efficacy and safety of sequential peeling with 70% GA and 20% SA as a monotherapy and as an adjuvant to systemic doxycycline in treatment of mild to moderate acne and the effect on serum interleukin (IL) 17 and tissue IL-1α.

Patients/methods: Forty-five mild to moderate acne vulgaris patients were randomly assigned into three groups.