The study investigates the relationship between thyroid hormones (THs) and kidney/heart function, particularly how TH deficiency impacts these organs.
It explores the potential benefits of vitamin D on renal and cardiac fibrosis in hypothyroid rats, comparing control, hypothyroid-only, and hypothyroid rats receiving vitamin D.
Results show that vitamin D supplementation significantly improved kidney and heart oxidative stress markers and reduced fibrosis, suggesting it could be a helpful treatment for such conditions.