Publications by authors named "Amir Shourideh"
Article Synopsis
- Resistance to cancer treatments like chemotherapy and immunotherapy poses major challenges in effective patient care.
- Redox homeostasis modification has shown promise in addressing this resistance by altering cellular signaling pathways.
- The study highlights mechanisms such as increased antioxidant activity, drug efflux alterations, and enhanced DNA repair that enable tumor cells to survive treatments, suggesting that better insights into these processes could lead to improved therapy outcomes.
Background: Liver hepatocellular carcinoma (LIHC) is a common cancer with a poor prognosis and high recurrence rate. We aimed to identify potential biomarkers for LIHC by investigating the involvement of hub genes, microRNAs (miRNAs), transcription factors (TFs), and protein kinases (PKs) in its occurrence.
Methods: we conducted a bioinformatics analysis using microarray datasets, the TCGA-LIHC dataset, and text mining to identify differentially expressed genes (DEGs) associated with LIHC.