Publications by authors named "Amir Reza Pashmineh Azar"
Polyethylene glycol-asparaginase (PEGAsp) is an established component of acute leukemia therapy. Hypersensitivity reactions to PEGAsp occur in 10% to 15% of patients, with polyethylene glycol suggested as the antigenic culprit. As coronavirus disease 2019 (COVID-19) mRNA vaccines contain polyethylene glycol, the safety of administration of these vaccines to patients with prior PEGAsp hypersensitivity has been questioned.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to improve the prediction of viable CD34+ hematopoietic progenitor cells (HPCs) for better engraftment in transplants, using a machine-learning model based on data collected on the day of apheresis.
- A retrospective review of 370 autologous HPC collections highlighted that 17% of products had a "poor" post-thaw index, with the XGBoost model showing the highest accuracy in predicting these losses.
- The findings indicated that considering post-thaw vCD34% improved engraftment times without necessitating extra collection days, suggesting a significant reduction in unnecessary procedures could be achieved with better predictive methods.