Efficacy of clarithromycin in pityriasis rosea.

Objective: To determine the efficacy of clarithromycin in the treatment of Pityriasis Rosea (PR).

Study Design: Double blind randomized controlled trial.

Place And Duration Of Study: Dermatology OPD, Military Hospital, Rawalpindi, from July 2008 to July 2009.

Multiple disseminated pyogenic granulomas.

Pyogenic granulomas (Granuloma telengiectaticum) or lobular capillary haemangioma are classically described as solitary lesions, occurring in young individuals, usually at the site of previous trauma, with a tendency to recur after treatment. We describe an unusual case of multiple disseminated pyogenic granulomas in an elderly male caucasoid of Pakistani origin in whom more than 400 lesions occurred de novo without any antecedent history of trauma or skin disease, responded well to treatment and showed no tendency for recurrence. Multiple eruptive pyogenic granulomas are probably a rare subset of the disease, which can occur at any age, arise de novo or in association with a skin or systemic disease and do not exhibit a tendency to recur after treatment.

Necrolytic acral erythema: successful treatment with topical tacrolimus ointment.

Necrolytic acral erythema is a relatively recently described psoriasis-like skin eruption seen in people infected with hepatitis C virus. Hepatitis C virus infection is endemic in many parts of the world with a steady increase of incidence in Pakistan. Recognition of this disorder is crucial to an early treatment of the underlying liver disease.