Publications by authors named "Amir L"

Background: Previously it was recognised onset of Lactogenesis II was delayed in women with Type I diabetes compared to women without diabetes, but the effect of gestational diabetes was unclear. Some clinicians suggest pregnant women with diabetes express breastmilk in late pregnancy to hasten onset of Lactogenesis II.

Aims: To confirm if Lactogenesis II occurs later in women with diabetes in pregnancy, and test if advice to express antenatally hastens Lactogenesis II.

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Connective tissue grafts for gingival recession treatment present significant challenges as they require an additional surgical site, leading to increased morbidity, extended operative times, and a more painful postoperative recovery for patients. Gelatin contains the arginine-glycine-aspartic acid (RGD) sequence, which supports cell adhesion and interactions. The development of gelatin hydrogels holds significant promise due to their biocompatibility, ease of customization, and structural resemblance to the extracellular matrix, making them a potential candidate for gingival regeneration.

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Previously, we reported the serious game as an innovative learning approach for an oral histology course. This study aimed to examine the impact of on summative assessment and the enablers and barriers factors affecting as an interactive learning strategy in an oral histology course. A crossover randomized controlled trial was performed.

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Article Synopsis
  • The study assessed how Research Ethics Committees (RECs) in seven Asian countries responded to the challenges posed by COVID-19 under tight timelines and public pressure.
  • A survey involving 688 REC members and 197 chairs/secretaries revealed that while most RECs had standard operating procedures, many lacked experience in reviewing COVID-19 related protocols, with 93% of members needing additional training.
  • SR-RECs demonstrated better adherence to ethical guidelines and faced more specific challenges in risk assessment and informed consent compared to NSR-RECs, highlighting the importance of established ethical review processes during health crises.*
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Background: Many individuals who experience preterm birth struggle with early breast milk supply, which can translate into suboptimal longer-term breastfeeding outcomes. Further investigations into the potential role of early non-pharmacological and pharmacological interventions in improving breast milk production soon after birth is growing. While natural galactagogues, such as brewer's yeast, are widely perceived by women to be safer than pharmaceutical galactagogues and are taken by many women, evidence to support their efficacy is largely absent.

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Objective: To examine longitudinal trends in clinical management of lactational mastitis in women attending general practice.

Design: Open cohort study.

Setting: Australian general practice using data from MedicineInsight.

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Undergraduate (UG) research is considered as an essential part of dental education. Numerous dental schools have included required course-based undergraduate research in their curricula. However, the implementation of UG research courses in the curriculum may vary between dental schools.

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Background: Mastitis is a common reason new mothers visit their general practitioner (GP). In Australia, the Therapeutic Guidelines: Antibiotic provides practical advice to GPs managing a range of infections, including mastitis. It is not known if Australian GPs prescribe antibiotics and order investigations as recommended for the management of mastitis.

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Background: Mothers of infants in most Sri Lankan neonatal units are required to be "inpatients" during the entirety of their infant's stay. This traditional practice is closely aligned to the relatively newer model of family-integrated care.

Purpose: Exploration of parent's views regarding the expectation for mothers to remain in hospital for the entire duration of their infant's neonatal unit stay.

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Problem: Low milk supply is the most common reason women give for stopping breastfeeding early and yet there is a lack of understanding about these women's experiences.

Background: Most women plan to breastfeed but many experience challenges such as low milk production, leading them to seek help and support.

Aim: To explore women's personal stories of how their low supply was discovered.

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Article Synopsis
  • - The study aimed to estimate the prevalence of breast characteristics indicating hypoplasia among women experiencing low milk supply during breastfeeding, alongside identifying related risk factors.
  • - Conducted through an online survey with 487 participants from various countries, findings revealed that a significant percentage exhibited atypical breast features, such as widely spaced breasts and stretch marks.
  • - Results indicated that about 68% reported at least one marker of hypoplasia, and being overweight during puberty was identified as a notable risk factor for these breast characteristics.
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Background: It is well known that breastfeeding plays an important role in the health of women and children. However, women are not always given optimal support and most do not reach their breastfeeding goals. About one in five, breastfeeding women report mastitis and a small proportion of these develop a breast abscess.

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Background: Women with diabetes in pregnancy have decreased exclusivity and duration of breastfeeding compared with women without diabetes, and their infants are at increased risk of hypoglycemia. Clinicians often suggest pregnant women with diabetes to express breastmilk, and studies have reported increased breastfeeding exclusivity in the early postnatal period for patients who have expressed. Little is known about longer term outcomes.

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Background: Oral histology is perceived by dental students as a challenging subject and often struggle to recognize the long-term relevance of understanding the cells and tissues at the microscopic level. Serious games have been reported to have a positive effect on student cognitive skills and learning motivation. However, there is still a limited amount of research supporting the effectiveness of serious games as a learning method in dentistry.

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Background: Hydrogel is considered a promising scaffold biomaterial for gingival regeneration. In vitro experiments were carried out to test new potential biomaterials for future clinical practice. The systematic review of such in vitro studies could synthesize evidence of the characteristics of the developing biomaterials.

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Article Synopsis
  • The RUBY trial found that a telephone-based peer support intervention significantly increased breastfeeding rates at 6 months compared to standard care for first-time mothers in Melbourne, Australia.
  • The cost-effectiveness analysis showed that the intervention cost $263.75 per mother, leading to an incremental cost-effectiveness ratio of $4146 per additional mother breastfeeding at 6 months, or $1393 if excluding volunteer time.
  • Overall, the intervention is suggested to be potentially cost-effective and valued highly by participants, advocating for its broader implementation.
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Importance: Ileocolic intussusception is an important cause of intestinal obstruction in children. Reduction of ileocolic intussusception using air or fluid enema is the standard of care. This likely distressing procedure is usually performed without sedation or analgesia, but practice variation exists.

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Background: Domperidone is one of the most commonly utilised pharmacological galactagogues, with evidence of increasing use in clinical practice. However, the use of domperidone as a galactagogue remains controversial, with mixed evidence on safety and efficacy, leading to variable clinical practice recommendations. We sought to evaluate contemporary patterns of domperidone use and examine maternal experiences related to perceived safety and effectiveness.

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Background: A host-protein score (BV score) that combines the circulating levels of TNF-related apoptosis-inducing ligand (TRAIL), interferon gamma-induced protein 10 (IP-10) and C-reactive protein (CRP) was developed for distinguishing bacterial from viral infection. This study assessed the potential of the BV score to impact decision making and antibiotic stewardship at the emergency department (ED), by comparing BV score's performance to physician's etiological suspicion at patient presentation.

Methods: Rosetta study participants, aged 3 months to 18 years with febrile respiratory tract infection or fever without source, were prospectively recruited in a tertiary care pediatric ED.

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Donor milk banks have strict donor screening criteria to ensure that donor milk is safe for premature or hospitalized babies. Yet little evidence is available to understand how potential donors, who are often breastfeeding their own infants, experience being ineligible ("deferred") to donate their milk to a milk bank. Interviews were conducted with 10 mothers who were permanently or temporarily deferred from donating to a large, not-for-profit milk bank in Australia.

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Fostering the growth, development, health, and wellbeing of children is a global priority. The early childhood period presents a critical window to influence lifelong trajectories, however urgent multisectoral action is needed to ensure that families are adequately supported to nurture their children's growth and development. With a shared vision to give every child the best start in life, thus helping them reach their full developmental potential, we have formed the International Healthy Eating Active Living Matters (HEALing Matters) Alliance.

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Undergraduate (UG) research is regarded as a fundamental component in dental education. The present study was designed to examine the perception of the clinical students and the graduates of dentistry profession programs in the past 10 years on UG research as a compulsory course at the Faculty of Dentistry Universitas Indonesia. A total of 310 respondents, consisting of clinical students (64.

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Molar incisor hypomineralisation (MIH) is a qualitative, dental enamel hypomineralisation defect affecting one to four first permanent molars, characterised by the present of asymmetries demarcated opacities, and is prevalent worldwide. An early diagnosis of MIH is crucial, to prevent further complications including the development of dental caries, hypersensitivity, pulp inflammation, and pain. Therefore, a thorough understanding of MIH is of clinical importance.

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Background: An important service system for rural parents experiencing complex trauma is primary health care.

Aim: To investigate workforce knowledge, attitudes and practices, and barriers and enablers to trauma-informed care in rural primary health care.

Material & Methods: This study used a descriptive, cross-sectional design.

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