Diabetic foot ulcer: A comprehensive review of pathophysiology and management modalities.

Diabetic foot ulcer (DFU) is a debilitating and severe manifestation of uncontrolled and prolonged diabetes that presents as ulceration, usually located on the plantar aspect of the foot. Approximately 15% of individuals with diabetes will eventually develop DFU, and 14%-24% of them will require amputation of the ulcerated foot due to bone infection or other ulcer-related complications. The pathologic mechanisms underlying DFU are comprise a triad: Neuropathy, vascular insufficiency, and secondary infection due to trauma of the foot.

Are Die-Hard Football or Other Sports Fans at Risk of Cardiovascular Events?

Trigger factors such as earthquakes, war, and terrorism have been shown to increase the risk of cardiovascular events in different studies. Similarly, strong emotions and psychological stress have been associated with myocardial infarction, symptomatic arrhythmias, and sudden cardiac death. Die-hard soccer, rugby, football, and baseball fans seem to be at risk of cardiac events, particularly in individuals with prior history of coronary artery disease.

Fish Oil Dilemma: Does It Increase the Risk of Ventricular Arrhythmias and Death? Can Fish Oil Kill You?

Omega-3-fatty-acids are now increasingly being used for potential beneficial anti-inflammatory effect in the treatment and management of cardiovascular disease. Eicosapentaenoic acid and Docosahexaenoic acid are 2 essential omega-3 fatty acids found predominately in fish and fish oil supplements. Despite the increased use of fish oil products for both primary and secondary prevention of cardiovascular morbidity and mortality, the available literature evidence are controversial.

Number of Pregnancies and Risk of Atrial Fibrillation.

Pregnancy is associated with major structural and hemodynamic changes in the cardiovascular system that predispose women to an increased risk of atrial fibrillation. While these changes generally resolve after parturition, the impact of subsequent pregnancies on the risk of atrial fibrillation is unknown. We searched through PubMed for studies that have investigated the impact of multiparity on the risk of atrial fibrillation.

Smoke and Heart Should Stay Apart: A Look at E Cigarettes and Other Alternatives to Conventional Cigarettes, and Their Impact on Cardiovascular Health.

The leading cause of preventable death in the world is smoking; leading to 7 million deaths attributable to tobacco use per year worldwide and 480,000 deaths per year in the United States. Though the actual rates of smoking in the United States have been on the decline, the advent of electronic cigarettes (E cigs) in 2007 was met with immense reception especially among the youth. Though initially thought to be a means to facilitate smoking cessation, recent evidence and the E cigs epidemic suggest its implications in significant morbidity and mortality.

The Face Is the Mirror of the Soul. The Cardiovascular Physical Exam Is Not Yet Dead!

Cardiac pathology can be congenital or acquired with underlying genetic predispositions. In this era of medicine there is a concern that the comprehensive physical examination doctors prided themselves on is becoming a lost art. Research studies have also revealed a decline in physical examination skills.