Publications by authors named "Amir Izadi"
Article Synopsis
- Breast cancer is the second most common cancer globally, significantly impacting women, with gene expression analysis used to guide prognosis and treatment.
- The study examined the expression of five specific genes (SIRT3, HRAS, LSP1, SCUBE2, and AP2A2) in 136 Iranian women with breast cancer, revealing varying expression levels among patients and controls.
- Key findings indicated that while SIRT3 levels were consistent, LSP1 was downregulated in patients, HRAS was overexpressed in tumors, and SCUBE2 showed increased expression, highlighting their potential as biomarkers and prognostic factors in breast cancer.
Background: Although the therapeutic effect of electroconvulsive therapy (ECT) on major depressive disorder is widely investigated, there is a gap in literature regarding the possible effects of the medications used for induction of anesthesia in ECT. To the best of the authors' knowledge, this study is the first randomized double-blind clinical trial comparing the effect of etomidate and sodium thiopental on the depression symptoms in patients who have received ECT.
Methods: The participants of this study are 60 adult patients with major depressive disorder who were referred for ECT.