Multiple hereditary exostosis syndrome is a rare diagnosis with approximately 1:50000 incidence prevailing in males. The exostoses or osteochondromas are benign but have the potential for malignant transformation in 1-5%. There is a strong genetic component, with exostosis (EXT) signaling pathways being an underlying cause.
View Article and Find Full Text PDFFuchs' endothelial corneal dystrophy (FECD) is progressive corneal endothelium dysfunction, characterised by corneal oedema, and potential blindness if left untreated. Keratoplasty is the only definitive treatment to restore vision in FECD, with different surgical techniques being described. The corneal transplant has been described as the most commonly performed and most successful allogenic transplant globally; therefore, it is crucial to dissect it further since a large proportion of the population worldwide is likely to be impacted.
View Article and Find Full Text PDFIntroduction Computed tomography (CT) scanning has become a fundamental aspect of many diagnostic pathways and therapeutic procedures. However, it is not without risk. Many patients are unaware of the exposure to ionising radiation that is involved with undergoing a CT scan, as well as the associated increase in cancer risk with cumulative exposure.
View Article and Find Full Text PDFDelayed facial nerve weakness secondary to head injury is rare. The mechanism of immediate facial nerve paralysis is obvious, however, the delayed presentation remains disputed. We report a 58-year-old gentleman who presents 6 days after being discharged following head trauma with a 2-day history of facial nerve paralysis (House-Brackmann grade 6).
View Article and Find Full Text PDFObjectives: To retrospectively analyse and report the utilisation of red blood cell (RBC) transfusion in a tertiary otolaryngology, head and neck centre in the United Kingdom.
Background: Twenty-seven per cent of RBC transfusions were for surgical indications in a 2014 England and North Wales survey. Currently, there is limited literature on RBC transfusions in Otolaryngology.
Background: Several treatment strategies for avoiding post-operative ileus have been evaluated in randomised controlled trials. This network meta-analysis aimed to explore the relative effectiveness of these different therapeutic interventions on ileus outcome measures.
Methods: A systematic literature review was performed to identify randomized controlled trials (RCTs) comparing treatments for post-operative ileus following colorectal surgery.
We report a case of large cell neuroendocrine carcinoma of the uterine cervix. A 33-year-old woman presented with a 4-month history of irregular vaginal bleeding and suspicious cervix. Transvaginal ultrasound showed a 3×3.
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