Publications by authors named "Amir Behrouzi"

Background: It is critical to examine the pathogenic pathways in coronavirus disease 2019 (COVID-19) that resulted in the development of severe lung injury. Surfactant protein B (SFTPB) is a vital component for sustaining life and serves pivotal functions in the host's defensive mechanisms and alveolar surface tension reduction. Our study aimed to determine the effect of SFTPB rs7316 and rs1130866 variants on the course of disease in COVID-19 patients.

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  • Replacing GnRH with pLH for ovulation synchronization in dairy cows led to improved pregnancy rates after artificial insemination without affecting blood progesterone levels.
  • In a study with 24 non-lactating Holstein cows, pLH treatment resulted in a longer duration of elevated LH compared to GnRH, though most morphological and cellular characteristics of the corpora lutea remained similar.
  • pLH-treated cows had higher in vitro progesterone production and increased oxytocin receptor mRNA levels, suggesting enhanced ovarian function and potential benefits for embryo development leading to higher pregnancy success rates.
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  • The study investigates how pre-natal nutrition and genetic potential for feed efficiency (RFI) affect DNA methylation in beef cattle, which could lead to better cattle breeding practices.
  • It specifically examines DNA methylation patterns in imprinted genes related to growth, with purebred Angus calves categorized by high and low RFI exposed to either a restricted or moderate maternal diet during gestation.
  • The findings indicate that low RFI steers exhibit higher methylation levels in certain genes compared to high RFI steers, particularly influenced by diet at specific growth stages, suggesting that nutrition can affect gene expression and potentially improve feed efficiency.
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  • The study aimed to investigate how common postpartum health issues are in dairy cows in Alberta and how these issues impact their milk production, reproduction, and survival rates.
  • 1096 Holstein cows from 11 dairy farms were monitored for health problems after calving, with 61% diagnosed with at least one issue and 25% having multiple disorders.
  • Cows with inflammatory issues faced lower milk production and fertility, while those with metabolic disorders had a higher risk of dying.
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The main objectives of this study were to determine the influence of diets enriched in α-linolenic, linoleic or oleic acid on the development and transcriptomic profile of embryos collected from dairy cattle. Non-lactating Holstein cows received one of the three diets supplemented with 8% rolled oilseeds: flax (FLX, n = 8), sunflower (SUN, n = 7) or canola (CAN, n = 8). After a minimum 35-day diet adaptation, cows were superovulated, artificially inseminated and ova/embryos recovered non-surgically after 7.

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In a previous work, using porcine LH (pLH) in lieu of GnRH for synchronizing ovulation in dairy cows improved pregnancy rates without increasing plasma progesterone concentrations after ovulation. The LH profile is known to remain elevated above basal concentrations (≥1 ng/mL) for up to 20 hours in pLH-treated cows compared to less than 6 hours in GnRH-treated cows. Because LH triggers a cascade of signaling networks in the preovulatory follicle to promote final maturation and support oocyte competence, we hypothesized that dissimilar LH profiles will differentially regulate the intrafollicular factors and expression of downstream genes associated with improved oocyte competence.

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