Publications by authors named "Amir Abd-Elhameed"
Article Synopsis
- Long-term diabetes can cause vascular problems, and this study explored how lncRNA LYPLAL1, miR-204-5p, and SIRT1 can serve as biomarkers for diagnosing diabetic microvascular complications (MVC).
- Researchers found that lncRNA LYPLAL1 and SIRT1 levels were lower in patients with MVC, while miR-204-5p levels were higher compared to those without MVC.
- The combination of these three markers showed 98.4% accuracy, with lncRNA LYPLAL1 being identified as a key independent predictor for MVC.
Ankylosing spondylitis (AS) is a chronic inflammatory disease that results in severe pain and stiffness in the joints. The causes and pathophysiology of AS are still largely unknown. The lncRNA H19 plays key roles in the pathogenesis of AS by mediating inflammatory progression by acting in the axis of IL-17A/IL-23.
View Article and Find Full Text PDFHypertension is a serious medical condition that can increase the risk of developing heart, brain, kidney, and other diseases. Many asymptomatic hypertension patients experience asymptomatic organ damage (AOD). The purpose of this study was to determine the roles of LncRNA-GAS5 and β-catenin in predicting AOD in hypertensive nondiabetic patients.
View Article and Find Full Text PDFIntroduction: Irritable bowel syndrome (IBS) is a gastrointestinal disorder due to enteric nervous system impairment that produces different patterns of digestion. IBS is a common finding in diabetic patients. The functions of lncRNAs in IBS are still not clear and need to be further investigated.
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