[Acquired bone marrow aplasia in children and young adults under the age of 30: Experience of the Pediatric Hematology and Oncology Department of the 20 August Hospital, Casablanca].

Bone marrow aplasia is a rare and serious hematologic disorder. Although benign, it is a hematologic disorder whose prognosis can be poor and whose spontaneous development can be fatal. Treatment is long, difficult and costly.

[Primary renal marginal zone B lymphoma].

Primary renal marginal zone B lymphoma is extremely rare. The renal involvement by the lymphoma is most often a manifestation of a disseminated disease. We report the case of a 53-year-old patient who presented lower back pain and kidney failure.

[Adult non-Hodgkin bone lymphomas].

Two forms of bone lymphomas can be distinguished: the primary bone lymphoma (PBL) and the secondary bone lymphoma (SBL). PBL is a rare disease with a good prognosis. Clinical manifestations and imaging findings are usually non-specific.

[Hepatocellular failure revealing T-cell large granular lymphocyte leukemia: Morocco case study and literature review].

In the last classification of the World Health Organization (WHO) 2016, T-cell large granular lymphocyte (LGL) leukemia is a type of mature natural killer T (NKT) cell lymphatic hematologic disease. T-LGL leukemia is characterized by CD3+ T-cell phenotype and TCR gene rearrangement (T lymphocyte receptor). It is a rare disease, mainly affecting people living in the Western world.

[œsotracheal fistula complicating primary mediastinal large B cell non-Hodgkin's lymphoma: a case study].

Primary mediastinal non-Hodgkin's lymphoma(PMNHL) is a rare cancer. Exceptionally, it can be complicated by tracheœsophageal fistulas, directly connecting the esophagus and the trachea and secondary to esophageal tumor or chemotherapy (hence the interest of our case). We report the case of a 24-year old Moroccan female patient, treated for primary mediastinal large B cell NHL revealed by dyspnœa associated with dysphagia and alteration of general condition.

[Epigastralgia revealing primary pancreatic large B-cell lymphoma in a young patient: about a case].

Primitive malignant pancreatic non-Hodgkin's lymphoma (NHL) is an extremely rare site of extranodal NHL, accounting for less than 0.7% of all NHLs and less than 0.5% of malignant pancreatic tumors.

[Severe acquired marrow aplasia and seronegative autoimmune hepatitis: a rare and serious association].

Post-hepatitis marrow aplasias are severe aplasias occurring in the six months following at least one episode of early onset hepatitis, usually seronegative for hepatitis viruses known. We report the case of a 28-year old patient with autoimmune hepatitis revealed by jaundice associated with hepatomegaly and hepatic cytolysis and confirmed by liver biopsy; four months later it was complicated by pancytopenia associated with severe marrow aplasia.

[Aggressive natural killer cell leukemia: study of a case occurred in Africa and literature review].

Aggressive natural killer cell leukemia (ANKL) is a disease entity within the spectrum of lymphoproliferative syndromes of NK cells. It is rare, preferentially affecting Asiatic people. It has been very rarely reported in the African population; hence the interest of our case.